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Our routes in Northwest Argentina: from Salta to Cafayate

Our routes in Northwest Argentina: from Salta to Cafayate

Sarah Johnson Sarah Johnson
4 minute read

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For Senior Product Executive Sarah and our co-founder and director Martin Johnson, travelling is all about exploring at their own pace. On their recent journey, Our routes in Northwest Argentina: from Salta to Cafayate they chose to experience the region by car, giving them the freedom to pause at viewpoints, take detours, and immerse themselves in the landscapes. From the city of Salta to the vineyards of Cafayate, their road trip was filled with dramatic scenery, colourful towns, and unforgettable moments.

Our routes in Northwest Argentina: from Salta to Cafayate


Our routes in Northwest Argentina: from Salta to Cafayate


Which destinations did you visit on your self-drive adventure?

Our adventure began in Salta and took us through Purmamarca, Salinas Grandes, Tilcara, Cachi, Molinos and finally Cafayate. Each destination had its own unique character, but the landscapes between them often stole the show.

Our routes in Northwest Argentina: from Salta to Cafayate

How did you make your way to Salta to begin the trip?

We flew with Air Europa via Madrid to Buenos Aires, spending two nights in the capital before catching a domestic Aerolineas Argentinas flight to Salta. The contrast between the lively streets of Buenos Aires and the peaceful mountains of Salta set the tone for an unforgettable trip.

Out of everywhere you visited, which location was your favourite and why?

The Quebrada de las Conchas was a highlight, a canyon of red rock formations that seemed to glow under the sun. The Devil’s Throat, a dramatic natural amphitheatre carved into the cliffs, was especially awe-inspiring.

The Quebrada de las Conchas

Was there a moment on the trip that felt particularly memorable?

Driving the dirt track from Cachi to Cafayate was an adventure in itself. With winding bends, lazy dogs napping by the roadside, and donkeys wandering freely, the journey felt alive with character. Stopping at Hacienda de Molinos for lunch in a shady courtyard made it even more memorable.

Road trip!

What advice would you give to someone planning a similar trip?

Altitude can be a challenge in this part of Argentina, with some roads climbing to over 4,000 metres. Weather can change quickly, and service stations are few and far between, so it’s wise to plan ahead. A good playlist is also essential – the perfect soundtrack for hours on the open road.

Misty scenes

What food and drink stood out most during your travels?

Argentina is famous for its wine, and the high-altitude Torrontés varietal was a new favourite. We enjoyed stand-out meals at El Cortijo in Cachi and House of Jasmines in Salta, while roadside empanadas at Parador Las Abritas provided the best kind of simple pleasure.

Roadside lunch stop

Do you have a favourite photo or video from your journey?

The Recta del Tin-Tin, a perfectly straight section of Route 33 surrounded by cacti and guanacos, captured the essence of our road trip. After navigating winding mountain roads, seeing this endless stretch of highway unfold before us was unforgettable.

The open road

Sum up your trip to Northwest Argentina in just three words?

Spectacular, peaceful, memorable.

Scenic parking spot


For Sarah and Martin, this self-drive through north-west Argentina was more than just a holiday – it was an adventure of freedom and discovery. The region’s landscapes are vast and varied, its towns full of character, and its people welcoming at every turn. Travelling by car offered the chance to see Argentina up close, on their own terms, with plenty of time to stop and savour the journey. It’s a route they would recommend to anyone seeking a mix of dramatic scenery, cultural encounters, and the joy of the open road.

If you enjoyed reading Our routes in Northwest Argentina: from Salta to Cafayate, why not check out our recommended holiday. Ready to start planning your adventure to Northwest Argentina?  Get in touch with one of our dedicated travel specialists here.

View our Northwest Argentina Self-Drive Holiday


FAQs

When is the best time of year to visit North-West Argentina?

The months from April to November are generally best. During this time the weather is more stable, skies are clearer, and there are fewer heavy rains that can make mountain passes or unpaved roads difficult. Summers (December to March) tend to bring more rainfall, which can cause flash flooding or road closures in the valleys.

Do I need a special vehicle for driving in this region?

A regular car works fine on many roads, especially paved highways. But for unpaved stretches (like parts of Ruta 40, high passes, or remote roads), a vehicle with decent ground clearance or 4WD is much safer. Renting something reliable with good suspension is a wise choice if you plan to cover dirt roads or mountainous terrain.

How much driving time should I allow between major stops?

Even if two places look close on a map, allow extra time. Roads are often winding, go through mountain passes, or may be unpaved. It’s common to allow 3–5 hours for what appear to be shorter distances. Plan for scenic stops, meals, and possible delays due to weather or road conditions.

What is altitude like, and how can I prepare for it?

Much of North-West Argentina is at high altitude. Some routes reach over 3,500–4,000 metres. That means thinner air, cooler nights, and the possibility of altitude sickness. To prepare, take it easy on your first day or two, stay hydrated, avoid strenuous activity straight away, and pack warm clothing for early mornings or evenings.

Is it safe to drive at night?

It is best to avoid driving long stretches after dark, especially on unfamiliar or unpaved roads. Lighting may be poor or non-existent in remote areas, animals often cross roads at night, and roadside assistance may be difficult to access.

How much cash should I carry, and do credit cards work everywhere?

Carry a reasonable amount of Argentine pesos in cash. Smaller towns, markets, and roadside stops may not accept cards, or only accept them with fees. ATMs can be limited in remote areas, so ensure you have enough cash for fuel, food, and any unexpected expenses.

What about fuel? Are petrol stations easy to find?

Fuel stations are fairly common along major highways and between larger towns. However, in remote stretches such as mountains, desert valleys, or high passes, they can be very scarce. Always fill up when you can, and plan your route so you are not caught short.

What should I pack for a self-drive in North-West Argentina?

Essentials include warm layers for evenings, sun protection (hat, sunglasses, sunscreen), sturdy walking shoes, a map or GPS with offline access, snacks, and plenty of water. A first aid kit, torch, and power bank are also useful, as conditions can change quickly.

Do I need permits or special registration for certain roads?

Most routes can be travelled freely. However, for some high mountain passes, border regions, or remote roads, authorities may require registration or permission. Always check with local tourism offices or your car rental company, and follow road signage and speed limits carefully.

What are the must-see highlights on a self-drive from Salta to Cafayate?

Key stops include the Quebrada de las Conchas, the winding stretch of Ruta 40 between Cachi and Cafayate, Purmamarca and the Hill of Seven Colours, Salinas Grandes, and charming towns like Molinos. Each adds a mix of scenery, culture, and relaxation.

What health precautions should I keep in mind?

Altitude can affect breathing and energy levels, so take time to acclimatise. Bring any personal medications, use sun protection, and drink bottled or filtered water where needed. Stick to well-prepared food in remote areas and avoid raw produce unless you are confident it is safe.

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